Browsing Ayan Roy by Title
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Adaptation of gut microbiome and host metabolic systems to lignocellulosic degradation in bamboo rats
(ISME, 2022)Bamboo rats (Rhizomys pruinosus) are among the few mammals that lives on a bamboo-based diet which is mainly composed of lignocellulose. However, the mechanisms of adaptation of their gut microbiome and metabolic systems ... -
Anisotine and amarogentin as promising inhibitory candidates against SARS-CoV-2 proteins: a computational investigation
(Taylor & Francis, 2020-09)The coronavirus disease 2019 (COVID-19) pandemic, caused by the novel severe acute respiratory syn- drome coronavirus 2 (SARS-CoV-2), presents an unprecedented challenge to global public health with researchers striving ... -
Codon usage signatures in the genus Cryptococcus: A complex interplay of gene expression, translational selection and compositional bias
(ELSEVIER, 2020)The fungal genus Cryptococcus comprises of several diverse species. The pathogens forming Cryptococcus neo- formans/ Cryptococcus gatti species complex are of immense clinical significance owing to the high frequency ... -
Comparative evolutionary genomics of Corynebacterium with special reference to codon and amino acid usage diversities
(CrossMark, 2018)The present study has been aimed to the com- parative analysis of high GC composition containing Corynebacterium genomes and their evolutionary study by exploring codon and amino acid usage patterns. Phyloge- netic ... -
Comparative genomics of Mycobacterium reveals evolutionary trends of M. avium complex
(ELSEVIER, 2018)Mycobacterium is gram positive, slow growing, disease causing Actinobacteria. Beside potential pathogenic spe- cies, Mycobacterium also contains opportunistic pathogens as well as free living non-pathogenic species. ... -
Comparative investigation of the various determinants that influence the codon and amino acid usage patterns in the genus Bifidobacterium
(CrossMark, 2015)Various strains of the genus Bifidobacterium are crucial members of the human, animal and insect gut, associated with beneficial probiotic activities. An extensive analysis on codon and amino acid usage of the GC ... -
Computational profiling of natural compounds as promising inhibitors against the spike proteins of SARS‐CoV‐2 wild‐type and the variants of concern, viral cell‐entry process, and cytokine storm in COVID‐19
(Wiley Periodicals LLC, 2022)The continuous spread and evolution of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), and the rapid surge in infection cases in the coronavirus disease 2019 (COVID‐19) evoke a dire need for ... -
Computational profiling of natural compounds as promising inhibitors against the spike proteins of SARS‐CoV‐2 wild‐type and the variants of concern, viral cell‐entry process, and cytokine storm in COVID‐19
(Wiley Periodicals LLC, 2022)The continuous spread and evolution of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), and the rapid surge in infection cases in the coronavirus disease 2019 (COVID‐19) evoke a dire need for ... -
Cyanobacterial metabolites as promising drug leads against the Mpro and PLpro of SARS-CoV-2: an in silico analysis
(Taylor & Francis, 2020)A novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) has emerged as the causative agent behind the coronavirus disease 2019 (COVID-19) pandemic. Treatment efforts have been severely impeded due to the ... -
A Database for Mycobacterium Secretome Analysis: ‘MycoSec’ to Accelerate Global Health Research
(OMICS, 2013)Members of the genus Mycobacterium are notorious for their pathogenesis. Investigations from various per- spectives have identified the pathogenic strategies employed by these lethal pathogens. Secretomes are believed to ... -
Elucidation of phytomedicinal efficacies of Clerodendrum inerme (L.) Gaertn. (Wild Jasmine)
(ELSEVIER, 2020)Clerodendrum inerme is a perennial shrub belonging to the family Lamiaceae and is used in many of the herbal preparations of Siddha and Ayurveda in India. Ethnomedicinally, the leaves of this plant are used to cure ... -
Environmental survival of SARS-CoV-2 – A solid waste perspective
(ELSEVIER, 2021)The advent of COVID-19 has kept the whole world on their toes. Countries are maximizing their efforts to combat the virus and to minimize the infection. Since infectious microorganisms may be transmitted by variety of ... -
Evolutionary complexities of swine flu H1N1 gene sequences of 2009
(ELSEVIER, 2009)A recently emerged novel influenza A (H1N1) virus continues to spread globally. The pandemic caused by this new H1N1 swine influenza virus presents an opportunity to analyze the evolutionary signif- icance of the origin ... -
Evolutionary Patterning of Hemagglutinin Gene Sequence of 2009 H1N1 Pandemic
(Taylor & Francis, 2012)The 2009 H1N1 swine flu is the first pandemic in decades. Infectivity of the influenza virus for human host depends largely on its ability to evade antibodies specific for viral protein called hemagglutinin (HA) that ... -
Evolutionary perspectives and adaptation dynamics of human seasonal influenza viruses from 2009 to 2019:an insight from codon usage
(ELSEVIER, 2021)The annually recurrent seasonal influenza viruses, namely, influenza A viruses (H1N1/pdm2009 and H3N2) and influenza B viruses, contribute substantially to human disease burden. Elucidation of host adaptation, population ... -
Hen raising helps chicks establish gut microbiota in their early life and improve microbiota stability after H9N2 challenge
(Microbiome, 2022)Background: Early gut microbial colonization is important for postnatal growth and immune development of the chicken. However, at present, commercial chickens are hatched and raised without adult hens, thus are cut off from ... -
HIV Progression Depends on Codon and Amino Acid Usage Profile of Envelope Protein and Associated Host-Genetic Influence
(frontiers in Micrology, 2017)Acquired immune deficiency syndrome (AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV). Two types of HIV have been characterized: HIV-1 and HIV-2. The present study ... -
Host Adaptation and Evolutionary Analysis of Zaire ebolavirus: Insights From Codon Usage Based Investigations
(frontiers in Micrology, 2020)Ebola virus (EBOV) has caused several outbreaks as the consequence of spillover events from zoonotic sources and has resulted in huge death tolls. In spite of considerable progress, a thorough know-how regarding EBOV ... -
Host Adaptive Evolution of Avian-Origin H3N2 Canine Influenza Virus
(frontiers in Micrology, 2021)Since its first isolation in around 2007, the avian-origin H3N2 canine influenza virus (CIV) has become established and continues to circulate in dog populations. This virus serves as a useful model for deciphering the ... -
Insights into the riddles of codon usage patterns and codon context signatures in fungal genus Puccinia, a persistent threat to global agriculture
(2018)The fungal genus Puccinia, comprising of several menacing pathogens, has been a persistent peril to global agriculture. Genome sequencing of various members of Puccinia offers a scope to excavate their genomic riddles. ...