| dc.description.abstract | Experiment was conducted on petroleum ether extract of a bark part of Averrhoa carambola in order to
find out various phytochemicals in this plant and to evaluate this plant’s cytotoxicity, ability to impede bacterial
growth and ability to work against harmful molecules like free radicals with the help of antioxidants that are
present in it. To make sure that the findings are accurate, a number of samples of this plant were collected from
different places of Bangladesh. Existence of flavonoid, carbohydrate, glycoside and steroid in the petroleum
extract of Averrhoa carambola was confirmed by conducting a phytochemical screening. The disc diffusion method,
where ten pathogenic bacteria were used, confirmed that the extract is capable of showing good action against
pathogenic organisms. But among these ten bacteria, the extract’s zone of inhibitions were comparatively larger in
cases of Salmonella typhi, Pseudomonas aeruginosa, Escherichia coli and Bacillus megaterium, which clearly indicates
that the extract is able to exhibit remarkable antibacterial action against these bacteria. The cytotoxic action of the
extract was measured by using the Brine Shrimp Lethality Bio-assay method. Using this method, the value of LC50
was calculated as 19.95. The extract’s phenolic content was estimated as 62.504 mg/g GAE, and the amount of
flavonoid in it was 24.107 mg/g of quercetin equivalent. A slight increase in the DPPH radical scavenging activity of
Averrhoa carambola was observed when the concentration of the extract was enhanced. In comparison to the IC50
value of 11.20μg/mL of ascorbic acid, which was considered as a reference in the test, the IC50 value of the plant
extract was estimated as 125.429μg/mL. | en_US |
